Global News and Digital Insights
for the Healthcare Industry

Day: May 18, 2022

Treatment of alcohol-use disorders and anxiety through gene editing

Research conducted on rats at the University of Illinois Chicago suggests that gene editing has the potential to treat anxiety-affected adults who were exposed to alcohol consumption in adolescence. The thesis of this research claims that during puberty and adulthood, our brain undergoes major epigenetic modifications such as the production of proteins associated with cognitive and emotional processes. However, binge-drinking of alcohol, unfortunately, disturbs normal development of the higher-order processes, rendering a person prone to anxiety and persistent alcoholism. The researchers claim that the gene editing experiment may be a potential treatment for people suffering from alcohol-use disorder. Read More from Big Think

Researchers at Columbia University develop organ-on-a-chip system

A multi-organ chip has been developed by scholars at the Columbia University School of Engineering and Applied Science. This chip has the capacity of incorporating tissues of various organs into independent slots that are further connected by simulated vascular flows. This technological tool will help scientists simultaneously diagnose effects of drug use and intervention on multiple organs. This will also assist in devising personalised medicine for patients as the engineered tissues are all created with the help of induced pluripotent stem cells. Although several such devices have been created, this technology stands out because creating communication among cells of different organs is a laborious task. Read More from Medagadget 

Food as Medicine (FAM) Programme to reduce food insecurity in New York

With the increase of food insecurity in the US, companies, such as Corbin Hill Food Project, are stepping forward to make healthy food accessible. Corbin Hill Food Project, a Harlem-based organisation, will implement Food as Medicine (FAM) programme in collaboration with Mount Sinai Health System and the Institute for Family Health’s Bronx Health REACH Project. Corbin Hill Food Project is the first firm in the US to have obtained a significant USDA FAM grant. The said programme aims to collect dietary health and behaviour data while also exploring household food insecurity. The objective of Corbin Hill Food Project is to lessen the use of healthcare and the cost related to it. Utilising a combination of decades of experience from the collaboration, FAM will bring fresh food produce to New Yorkers. Read More from Mount Sinai

Horizon’s Uplizna cleared by EC for neuromyelitis optica spectrum disorder (NMOSD)

European Commision (EC) has approved Horizon’s Uplizna as a monotherapy in adults for the treatment of Neuromyelitis optica spectrum disorder (NMOSD), a disease affecting the central nervous system (CNS), specifically the optic and spinal nerve. The treatment is viable for NMSOD patients who are anti-aquaporin-4 immunoglobulin G seropositive. Following the preliminary doses, experiments explicated that Uplizna greatly reduced NMOSD attacks with two infusions per year. 87.6% of the subjects chosen for trial remained attack free for 28 weeks. After EC’s nod, Uplizna is fit to be used in all European states as well as Iceland, Liechtenstein and Norway. Read More from Pharmaceutical Technology

Overjet’s AI-based platform will now assist dentists in detecting cavities

Overjet, a Boston-based firm, has claimed that FDA has approved its AI-powered software, Caries Assist, in the diagnoses of cavities. Overjet has expanded its platform in dentistry as previously, the software had been approved for the treatment of gum disease. Caries Assist has shown promising results during experimentation. The software has increased the accuracy rate by 32%, as compared to human diagnosis, through AI-assisted data analysis. With the help of this innovation, orthodontics will observe less ‘missed cavity’ cases. Although companies like VideaHealth also employs AI, Overjet claims to stand out as it detects gum disease as well as cavities. Read More from MedCity News

Machine Learning tool to be adopted by scientists to identify long-COVID

The Lancet Digital Health published research that informed that XGBoost machine learning models used by the National COVID Cohort Collaborative have proved to be more efficient and accurate in identifying long-COVID. The research findings at The Lancet Digital Health have the potential to improve clinical research which will help healthcare providers to put forth a more effective care regimen to the affected individuals. Since it has been difficult to identify long-COVID, data analysis tools such as N3C have been employed to devise the machine learning tool that is better at detecting symptoms, risk factors, and introducing treatments. Read More from UNC Healthcare

Treatment of alcohol-use disorders and anxiety through gene editing

Research conducted on rats at the University of Illinois Chicago suggests that gene editing has the potential to treat anxiety-affected adults who were exposed to alcohol consumption in adolescence. The thesis of this research claims that during puberty and adulthood, our brain undergoes major epigenetic modifications such as the production of proteins associated with cognitive and emotional processes. However, binge-drinking of alcohol, unfortunately, disturbs normal development of the higher-order processes, rendering a person prone to anxiety and persistent alcoholism. The researchers claim that the gene editing experiment may be a potential treatment for people suffering from alcohol-use disorder. Read More from Big Think

Researchers at Columbia University develop organ-on-a-chip system

A multi-organ chip has been developed by scholars at the Columbia University School of Engineering and Applied Science. This chip has the capacity of incorporating tissues of various organs into independent slots that are further connected by simulated vascular flows. This technological tool will help scientists simultaneously diagnose effects of drug use and intervention on multiple organs. This will also assist in devising personalised medicine for patients as the engineered tissues are all created with the help of induced pluripotent stem cells. Although several such devices have been created, this technology stands out because creating communication among cells of different organs is a laborious task. Read More from Medagadget 

Food as Medicine (FAM) Programme to reduce food insecurity in New York

With the increase of food insecurity in the US, companies, such as Corbin Hill Food Project, are stepping forward to make healthy food accessible. Corbin Hill Food Project, a Harlem-based organisation, will implement Food as Medicine (FAM) programme in collaboration with Mount Sinai Health System and the Institute for Family Health’s Bronx Health REACH Project. Corbin Hill Food Project is the first firm in the US to have obtained a significant USDA FAM grant. The said programme aims to collect dietary health and behaviour data while also exploring household food insecurity. The objective of Corbin Hill Food Project is to lessen the use of healthcare and the cost related to it. Utilising a combination of decades of experience from the collaboration, FAM will bring fresh food produce to New Yorkers. Read More from Mount Sinai

Horizon’s Uplizna cleared by EC for neuromyelitis optica spectrum disorder (NMOSD)

European Commision (EC) has approved Horizon’s Uplizna as a monotherapy in adults for the treatment of Neuromyelitis optica spectrum disorder (NMOSD), a disease affecting the central nervous system (CNS), specifically the optic and spinal nerve. The treatment is viable for NMSOD patients who are anti-aquaporin-4 immunoglobulin G seropositive. Following the preliminary doses, experiments explicated that Uplizna greatly reduced NMOSD attacks with two infusions per year. 87.6% of the subjects chosen for trial remained attack free for 28 weeks. After EC’s nod, Uplizna is fit to be used in all European states as well as Iceland, Liechtenstein and Norway. Read More from Pharmaceutical Technology

Overjet’s AI-based platform will now assist dentists in detecting cavities

Overjet, a Boston-based firm, has claimed that FDA has approved its AI-powered software, Caries Assist, in the diagnoses of cavities. Overjet has expanded its platform in dentistry as previously, the software had been approved for the treatment of gum disease. Caries Assist has shown promising results during experimentation. The software has increased the accuracy rate by 32%, as compared to human diagnosis, through AI-assisted data analysis. With the help of this innovation, orthodontics will observe less ‘missed cavity’ cases. Although companies like VideaHealth also employs AI, Overjet claims to stand out as it detects gum disease as well as cavities. Read More from MedCity News

Machine Learning tool to be adopted by scientists to identify long-COVID

The Lancet Digital Health published research that informed that XGBoost machine learning models used by the National COVID Cohort Collaborative have proved to be more efficient and accurate in identifying long-COVID. The research findings at The Lancet Digital Health have the potential to improve clinical research which will help healthcare providers to put forth a more effective care regimen to the affected individuals. Since it has been difficult to identify long-COVID, data analysis tools such as N3C have been employed to devise the machine learning tool that is better at detecting symptoms, risk factors, and introducing treatments. Read More from UNC Healthcare